I am having the same/similar problem rendering the program unusable. I rebooted the computer but the problem is still there.
When I open RM I get a message that Ancestry is not responding [Retry]. Clicking Retry causes the dialog box to go away. When I try to close the program I get the usual back up or skip option, but then the program locks up from there and has to be killed via the task manager.
Attempting to disconnect from Ancestry tree produces the same result initially but after a hard kill I can now open and close the program.