2 replies to this topic

[BRM]

I have MtDNA information from FamilyTreeDNA for my Dad who is deceased.   There is a fact for entering DNA information. Entering the Haplogroup was straight forward. , but I am confused on how to enter the HVR1 and HVR2 data that refers to locations.  The RootsMagic DNA fact for mtDNA just asks for a list of locations for HVR1 and HVR2 and I don't know what should be entered.

 

Has anyone else used or tried to use this fact?  See notes below.

 

In the FamilyTreeDNA mTDNA results, there is information on differences for the HVR1 and HVR2 from RSRS as noted in the format below,

 

Extra Mutations

309.1C

309.2C

315.1C

522.1A

522.2C

C14142T

C16519T

Missing Mutations

A16129G

HVR1 DIFFERENCES FROM RSRS

• T16187C
• C16189T
• T16223C
• G16230A
• T16278C
• T16304C
• C16311T
• C16519T

HVR2 DIFFERENCES FROM RSRS

• G73A
• C146T
• C152T
• C195T
• A247G
• 309.1C
• 309.2C
• 315.1C
• C456T
• 522.1A
• 522.2C

CODING REGION DIFFERENCES FROM RSRS

• A769G
• A825t
• A1018G
• G2706A
• A2758G
• C2885T
• T3594C
• G4104A
• T4312C
• T4336C

 

or there is rCRS information for HVR1 and HVR2 Reference Sequences with positions and results at those positions, as well as CR Sequence locations and results 

  

HVR1 DIFFERENCES FROM rCRS

• 16129A
• 16304C

HVR2 DIFFERENCES FROM rCRS

• 263G
• 309.1C
• 309.2C
• 315.1C
• 456T

CODING REGION DIFFERENCES FROM rCRS

• 750G
• 1438G
• 4336C
• 4769G
• 5839T
• 8860G
• 14142T
• 15326G

Revised Cambridge Reference Sequence

HVR1 REFERENCE SEQUENCE

Show All Positions Position CRS Your Result 16129 G A 16304 T C

HVR2 REFERENCE SEQUENCE

Show All Positions Position CRS Your Result 263 A G 309.1   C 309.1   C 315.1   C 456 C T

CR REFERENCE SEQUENCE

Show All Positions Position CRS Your Result 750 A G 1438 A G 4336 T C 4769 A G 5839 C T 8860 A G

 

[TomH]

I haven't done DNA so my comments may be ill informed but from what I have seen, the RootsMagic DNA fact is useful only as a place to store some data. That which does not fit the form I would put into the Note (either or both the fact and the source). Beyond that, the RM fact is currently useless. It cannot be transferred to another database via GEDCOM or drag'n'drop and it cannot be outputted in any report nor compared with any other person's DNA fact. AFAIK, the only way to retrieve what you put into the fact is on screen in the Edit Person window. I would use the fact to record that a test was done and tag the test results as a source, webtag to where it is stored online, ...

[lpasher]

I had my dad tested at Family Tree DNA as well.  I used the rCRS values shown under HVR1 and HVR2 differences.  Those are the values that appear on the "certificate" that you can print, and the certificate states "The letters designate the base that occurs at each of those positions in place of the entire CRS. These are distinctive of this sample and may be compared to other people to confirm or rule out common descent, providing genetic evidence of genealogical relationships."  Since those are the distinctive ones used for comparison, I figured those would be the best to enter into the RM DNA test results.  My "logical" thinking is that if RM ever did introduce DNA matching/comparison, those would be the values used.